June 2 (Reuters) - Wall Street's main indexes opened lower on Tuesday after hitting a series of record highs, while blowout results from Hewlett Packard Enterprise ( HPE ) and a funding commitment from Alphabet underscored investor confidence in the AI buildout.

The Dow Jones Industrial Average fell 166.0 points, or 0.33%, at the open to 50,912.84. The S&P 500 fell 4.6 points, or 0.06%, at the open to 7,595.4​, while the Nasdaq Composite dropped 56.7 points, or 0.21%, to 27,030.072 at the opening bell.

(Reporting by Medha Singh in Bengaluru; Editing by Devika Syamnath)