12:18 PM EDT, 07/16/2025 (MT Newswires) -- European stock markets closed mixed in Wednesday trading as the Stoxx Europe 600 fell 0.57%, Germany's DAX declined 0.21%, the FTSE 100 was off 0.13%, France's CAC slumped 0.57%, and the Swiss Market Index was up 0.08%.

The euro area registered a 16.2 billion-euro ($18.9 billion) surplus in trade in goods with the rest of the world in May, compared with 12.7 billion euros in May 2024, according to the EU's statistical office Eurostat. Analysts expected 13.9 billion, according to Bloomberg.

The euro area exports of goods to the rest of the world totaled 242.6 billion euros, a 0.9% increase compared with May 2024. Meanwhile, imports from the rest of the was 226.5 billion euros, down 0.6% from a year earlier.

In the UK, annual inflation rose 3.6% in June, up from 3.4% in May, according to the Office for National Statistics. Analysts were expecting a 3.4% increase, according to Bloomberg. Increasing prices for transport, particularly motor fuels, spurred the rise.

And in corporate news, Stellantis said Wednesday that it decided to discontinue its hydrogen fuel cell technology development due to market concerns.

The European automaker said it does not expect the adoption of hydrogen-powered commercial vehicles before the end of the decade due to the limited refueling infrastructure, high capital requirements, and the need for better buyer incentives.

British pharmaceutical company AstraZeneca said Wednesday that its phase 3 trial for its experimental therapy anselamimab in patients with advanced light chain amyloidosis did not meet its primary endpoint compared to placebo.

The company said the trial's main goal was a hierarchical combination of time to all-cause mortality and frequency of cardiovascular hospitalizations.

Dutch semiconductor company ASML reported fiscal Q2 earnings Wednesday of 5.90 euros ($6.86) per diluted share, up from 4.01 euros a year earlier. Analysts polled by FactSet expected 5.24 euros.

Sales for the quarter ended June 29 were 7.69 billion euros, up from 6.24 billion euros a year earlier. Analysts polled by FactSet expected 7.55 billion euros.

British mining company Rio Tinto said Wednesday that it incurred $300 million of gross costs associated with US tariffs on its primary aluminum exports from Canada in H1.

Among active shares, French carmaker Renault fell by as much as 18% in Paris on Wednesday after the company lowered its 2025 guidance and announced the appointment of a new interim chief executive officer.