11:05 AM EST, 01/22/2025 (MT Newswires) -- European equities traded in the US as American depositary receipts were slightly lower late Wednesday morning, declining 0.14% to 1,346.88 on the S&P Europe Select ADR Index.

From continental Europe, the gainers were led by semiconductor company Sequans Communications ( SQNS ) and biopharmaceutical firm DBV Technologies ( DBVT ) , which rose 3.3% and 2.1%, respectively. They were followed by software firm SAP (SAP) and internet advertising company Criteo ( CRTO ) , which were up 1.8% and 1.6%, respectively.

The decliners from continental Europe were led by furniture maker Natuzzi (NTZ) and pharmaceutical company Ascendis Pharma ( ASND ) , which fell 6.4% and 5.7% respectively. They were followed by biotech firm Evaxion Biotech ( EVAX ) and biopharmaceutical company Genfit ( GNFT ) , which lost 4% and 3.7% respectively.

From the UK and Ireland, the gainers were led by biopharmaceutical companies Biodexa Pharmaceuticals ( BDRX ) and Adaptimmune Therapeutics ( ADAP ) , which increased 3.3% and 0.9% respectively. They were followed by biopharmaceutical company NuCana ( NCNA ) and hospitality company InterContinental Hotels Group ( IHG ) , which were up 0.8% and 0.7% respectively.

The decliners from the UK and Ireland were led by biopharmaceutical companies Bicycle Therapeutics ( BCYC ) and Akari Therapeutics ( AKTX ) , which dropped 6.4% and 3.5% respectively. They were followed by biopharmaceutical company Mereo BioPharma Group ( MREO ) and utilities company National Grid ( NGG ) , which were down 2.3% and 2.1% respectively.