11:09 AM EST, 02/12/2025 (MT Newswires) -- European equities traded in the US as American depositary receipts were treading water late Wednesday morning, edging 0.03% lower to 1,397.50 on the S&P Europe Select ADR Index.

From continental Europe, the gainers were led by pharmaceutical company Ascendis Pharma ( ASND ) and furniture maker Natuzzi (NTZ), which rose 3.4% and 2.5%, respectively. They were followed by brewing company Anheuser-Busch InBev ( BUD ) and financial services company Banco Santander (SAN), which were up 2% and 1.8%, respectively.

The decliners from continental Europe were led by accommodations booking company trivago (TRVG) and biotech firm Evaxion Biotech ( EVAX ) , which fell 8.9% and 4.3% respectively. They were followed by semiconductor company Sequans Communications ( SQNS ) and petroleum refiner Equinor ( EQNR ) , which dropped 4.2% and 3% respectively.

From the UK and Ireland, the gainers were led by insurance company Prudential (PUK) and biopharmaceutical company Verona Pharma ( VRNA ) , which advanced 6.6% and 4.6% respectively. They were followed by biopharmaceutical companies Bicycle Therapeutics ( BCYC ) and Amarin ( AMRN ) , which increased 2.7% and 2.3% respectively.

The decliners from the UK and Ireland were led by biopharmaceutical companies NuCana ( NCNA ) and Biodexa Pharmaceuticals ( BDRX ) , which lost 2.7% and 2.6% respectively. They were followed by utilities company National Grid ( NGG ) and communications company WPP ( WPP ) , which were down 2% each.