TOKYO, May 7 (Reuters) - Japan's Nikkei share average

ticked lower on Wednesday, threatening to end a seven-session

winning streak, as pharmaceutical shares led losses after U.S.

President Donald Trump said he would reveal tariffs on drugs

over the next two weeks.

Automaker stocks slumped as Japanese investors returned from

a four-day weekend to an overall stronger yen, cutting the value

of overseas revenues. Sony Group ( SONY ), which runs a movie

studio, sank following Trump's announcement of a 100% levy on

foreign-made films.

Tariff worries overshadowed any improvement in market

sentiment kindled by news that U.S. Treasury Secretary Scott

Bessent and chief trade negotiator Jamieson Greer will meet

China's economic tsar, He Lifeng, in Switzerland this weekend

for talks.

Investors were also reluctant to push the Nikkei above

Friday's five-week peak before the conclusion of the Federal

Reserve's two-day policy meeting later in the day.

With so many issues regarding tariffs still unresolved,

investors are not in a position to chase the market higher, said

Nomura strategist Fumika Shimizu.

"The seven-day rally may be acting as a weight on the

market."

The Nikkei ended the morning session down 0.05%

after fluctuating in a very narrow range on either side of

Friday's closing level.

The biggest drags on the index included Sony ( SONY ) and drugmaker

Terumo ( TRUMF ), along with heavily weighted Uniqlo operator

Fast Retailing ( FRCOF ). Sony ( SONY ) lost 3.4%, Terumo ( TRUMF ) declined 2.3%

and Fast Retailing ( FRCOF ) shed 1.5%.

Overall, though, the Nikkei's performance was fairly

balanced, with 120 of its 225 components rising, 101 falling and

four flat.

The broader Topix, by contrast, rose 0.4%.

The Nikkei's biggest decliner in percentage terms was

Sumitomo Pharma ( DNPUF ), which slumped 6.7%. Peers Otsuka

Holdings ( OTSKY ) and Eisai ( ESALF ) rounded out the bottom

three, dropping 4.9% and 4.4% respectively.

Mitsubishi Motors ( MMTOF ) was the worst-faring automaker,

sliding 2.7%. Toyota ( TM ) lost 2.1% ahead of its earnings

release on Thursday.

Trading houses were a bright spot after Berkshire Hathaway

affirmed its commitment to investments in those businesses even

as Warren Buffett stepped aside as CEO.

Marubeni ( MARUF ) jumped 5.8% and Mitsubishi Corp ( MSBHF )

advanced 3.4%.