NEW YORK, June 6 (Reuters) - Drugmaker Eli Lilly
presented trial results to medical professionals on Saturday
showing its next-generation obesity drug retatrutide curbed
sleep apnea severity in addition to boosting weight loss and
helping knee pain.
* In a Phase 3 trial, Lilly found a weekly injection of
retatrutide reduced moderate-to-severe obstructive sleep apnea
severity by 60.6% in adults with obesity. Lilly's older drug
Zepbound is approved for the condition.
* In the same trial, the drug reduced knee osteoarthritis
pain by up to 73.1%, Lilly found. The results were presented at
an American Diabetes Association conference in New Orleans.
* Lilly previously disclosed results of the two studies
presented on Saturday showing patients with obesity lost 28% of
body weight and adults with type 2 diabetes experienced
significant drops in blood sugar levels.
* In one of the studies, 2% of patients with diabetes who
took the lowest dose of the drug experienced major adverse
cardiovascular events. Such events were not necessarily caused
by the drug, according to detailed results published in the
Lancet on Saturday.
* Retatrutide is Lilly's experimental "triple G" drug, which
targets GLP-1, a second obesity-related hormone called GIP and
the body's receptors for a third hormone called glucagon.
* The Indiana-based company and rivals including Denmark's
Novo Nordisk are in a race to dominate the booming
market for obesity and diabetes drugs.