March 7 (Reuters) - Eli Lilly ( LLY ) said on Thursday
it has found bacteria and high levels of impurities in products
claiming to be compounded versions of tirzepatide, the active
ingredient in its popular diabetes drug Mounjaro and weight loss
treatment Zepbound.
The U.S. drugmaker has sued several medical spas,
weight-loss clinics and compounding pharmacies to stop them from
selling products purporting to contain tirzepatide.
Compounded drugs are custom-made medicines based on the same
ingredients as branded versions, and often cheaper, but also
subject to less regulatory scrutiny.
In an open letter, Lilly said some of these products had a
different chemical structure as well as a different color than
the approved versions of Mounjaro or Zepbound.
"In at least one instance, the product was nothing more than
sugar alcohol," Lilly said.
The Alliance for Pharmacy Compounding, which represents
compounding pharmacists and technicians, did not immediately
respond to a request for comment.
The United States allows licensed pharmacies to legally
produce compounded drugs when the branded version of a drug is
in short supply.
Lilly, however, said it does not sell or provide tirzepatide
to any compounding pharmacies.
Danish rival Novo Nordisk has also taken legal
action against those offering products that claim to contain
semaglutide, the active ingredient in its popular weight loss
drug, Wegovy.
Novo reported in December it had found some samples of
compounded semaglutide to be up to 33% impure.
(Reporting by Bhanvi Satija in Bengaluru; Editing by Shinjini
Ganguli)