July 27 (Reuters) -
Swiss drugmaker Roche Holding plans to investigate
whether an experimental medicine can delay or prevent
Alzheimer's disease symptoms, it said on Sunday, as a part of
the company's growing development programme for the disease.
The clinical trial of the drug, Trontinemab, will target
people who are at risk of cognitive decline and will aim to
delay or prevent the symptoms of Alzheimer's, Roche said in a
statement.
Trontinemab is designed so that the drug is transported
across the blood brain barrier-protective blood vessels that
prevent chemicals in the bloodstream from entering the brain -
in hopes of delivering more of the treatment to the brain.
Rivals like Eli Lilly ( LLY ) have been making progress
in the complicated field of Alzheimer's recently, with Lilly's
drug Kisunla getting a recommendation for approval for certain
patients from the European Medicines Agency last week. Kisunla
is already approved in the U.S.
Treatments for Alzheimer's approved so far, including
Eisai ( ESALF ) and Biogen's Leqembi and Lilly's
Kisunla, are designed to clear sticky clumps of a protein called
amyloid beta in the brain. They carry hefty price tags as well
as the risk of serious brain swelling and bleeding.