NEW YORK, Jan 13 (Reuters) - Medical data research
company Truveta said on Monday that Regeneron Pharmaceuticals ( REGN )
, Illumina ( ILMN ) and 17 U.S. health systems will take
a $320 million stake in the company as part of a deal to build
the world's largest genetic database.
The deal values privately held Truveta at more than $1
billion, it said. Biotechnology company Regeneron pledged to put
in $120 million and genetic sequencing company Illumina ( ILMN )
is investing $20 million.
The rest will come from U.S. health systems including New
York-based Northwell Health, multi-state non-profit Trinity
Health and Advocate Health, based in Chicago.
The project aims to accumulate 10 million genomic sequences
relatively quickly, a move the parties said would accelerate
drug discovery and transform patient care.
"This is knowledge we just don't have," said Truveta CEO
Terry Myerson. "We don't know today why some people get lung
cancer and have never smoked. We spend billions of dollars a
year in colonoscopies on people that will never get colon
cancer."
Genetic sequencing can help indicate patient predispositions
for diseases like Alzheimer's and sickle cell, aiding in drug
development, or identify mutations associated with cancer or
other diseases that a particular drug may target effectively.
"The scale and diversity of the Truveta Genome Project will
enable us to explore the complex interplay between genetics and
health in unprecedented detail," Regeneron executive Aris Baras,
said in a press release.
During routine lab tests, the project's healthcare partners
will ask patients to consent to analysis of their leftover
specimens and link them to anonymous medical records. Regeneron
will sequence the genomes.
The genetic data will then be stored with Truveta Data to
support biological analysis.
Myerson expects the project to eventually have more patient
diversity than the two largest existing genetic databases, the
U.S. National Institutes of Health's All of Us Research Program
and the UK Biobank. Those databases represent 850,000 and
500,000 participants, respectively, according to their websites.
When entities pay Truveta to use its anonymous patient
data, the company will reimburse providers. "That reimbursement
provides an economic incentive for them to make the project
work," the CEO said.
Technology giant and previous Truveta investor Microsoft ( MSFT )
will provide the project with cloud storage through its
Azure software, according to the release.