The Dow Jones index closed lower by over 400 points on Wednesday. When insiders purchase or sell shares, it indicates their confidence or concern around the company's prospects. Investors and traders interested in penny stocks can consider this a factor in their overall investment or trading decision.

Below is a look at a few recent notable insider transactions for penny stocks. For more, check out Benzinga's insider transactions platform.

Dominari Holdings

The Trade: Dominari Holdings Inc ( DOMH ) President Kyle Michael Wool acquired a total of 8,500 shares an average price of $2.99. To acquire these shares, it cost around $25,390.

What's Happening: On April 1, Dominari Holdings ( DOMH ) posted a narrower quarterly loss.

What Dominari Holdings Does: Dominari Holdings Inc ( DOMH ) is a biotechnology company with a diverse portfolio of small-molecule anticancer and antiviral therapeutics in development.

BioRestorative Therapies

The Trade: BioRestorative Therapies Inc ( BRTX ) Director, VP of Research and Development Francisco Silva acquired a total of 8,308 shares at at an average price of $1.23. To acquire these shares, it cost around $10,229.

What's Happening: On April 8, BioRestorative Therapies ( BRTX ) partnered with Galen Patient Recruitment to accelerate completion of enrollment in Phase 2 trial of BRTX-100 in chronic lumbar disc disease.

What BioRestorative Therapies Does: BioRestorative Therapies Inc ( BRTX ) is a biotechnology company based in the United States.

Check This Out: Jim Cramer Says WESCO International Is A Buy, Recommends Buying This Stock Under $20

Lion Copper and Gold

The Trade: Lion Copper and Gold Corp ( LCGMF ) Director Tony L Alford acquired a total of 5,072,683 shares at an average price of $0.06. The insider spent around $309,296 to buy those shares.

What's Happening: The company's stock gained around 6% over the past month.

What Lion Copper and Gold Does: Lion Copper and Gold Corp ( LCGMF ) is a Canadian mineral exploration company that is engaged in the acquisition, exploration, and development of copper projects in Nevada, Alaska, and Montana in the United States and British Columbia, Canada.

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