04:57 PM EDT, 05/13/2025 (MT Newswires) -- US equity indexes ended mixed Tuesday as Wall Street digested official April inflation data, while technology stocks advanced led by Nvidia ( NVDA ) .

The Nasdaq Composite rose 1.6% to 19,010.1, while the S&P 500 climbed 0.7% to 5,886.6. The Dow Jones Industrial Average dropped 0.6% to 42,140.4. Among sectors, technology paced the gainers, with a 2.3% jump, while health care saw the biggest drop of 3%.

In economic news, US consumer prices rebounded last month, but missed Wall Street's estimates, while annual inflation eased to the lowest level since February 2021, the Bureau of Labor Statistics said.

"There isn't a lot of evidence of tariffs boosting the (consumer price index) in April, but this shouldn't be surprising as it takes time," Oxford Economics said. "The areas where tariffs likely boosted prices in April were in furniture/bedding, appliances, and to a lesser extent toys."

The US and China recently reached an agreement on a 90-day suspension of reciprocal duties. The two countries had been in a trade war since President Donald Trump's announcement of sweeping new tariffs early last month.

The official US producer prices report for April is scheduled to be released Thursday.

Small business optimism in the US deteriorated for a fourth consecutive month in April as owners continue to grapple with macro uncertainty, a survey by the National Federation of Independent Business showed Tuesday.

Uncertainty remained "a major impediment" for owners in April, impacting hiring plans, investment decisions and other aspects of business, NFIB Chief Economist Bill Dunkelberg said.

US Treasury yields were mixed, with the 10-year rate edging higher by 0.9 basis point to 4.48% and the two-year rate easing 1.6 basis points to 4.02%.

Nvidia ( NVDA ), Amazon ( AMZN ) , Alphabet's (GOOG, GOOGL) Google ( GOOG ) and Advanced Micro Devices ( AMD ) announced separate partnerships with Humain, an artificial intelligence company backed by Saudi Arabia's Public Investment Fund.

Nvidia ( NVDA ) shares were up 5.6%, the top gainer on the Dow and among the best on the S&P 500. AMD gained 4%. Amazon ( AMZN ) was up 1.3%, while Alphabet's class C and A shares gained 0.8% and 0.7%, respectively.

The announcements come as the White House said Tuesday that Saudi Arabia will invest $600 billion in the US, initially focusing on areas including energy, defense, technology and critical minerals. Trump arrived in Riyadh on Tuesday, with plans to visit Qatar and the United Arab Emirates later in the week.

First Solar ( FSLR ) shares surged 23%, the top performer on the S&P 500, as Wolfe Research upgraded the stock to outperform from peer perform.

UnitedHealth Group ( UNH ) suspended its full-year outlook amid higher-than-expected medical costs, while the health insurance giant said that Andrew Witty stepped down as chief executive due to "personal reasons." The company's shares slumped 18%, the worst performer on the Dow and the S&P 500.

Coinbase Global ( COIN ) shares soared 24%. The stock's upcoming inclusion in the S&P 500 is expected to help boost institutional ownership in the cryptocurrency exchange, Oppenheimer said.

West Texas Intermediate crude oil was up 2.7% at $63.65 a barrel.

Gold rose 0.8% to $3,253.90 per troy ounce, while silver added 1.5% to $33.12 per ounce.