03:49 PM EDT, 03/21/2025 (MT Newswires) -- Health care stocks fell late Friday afternoon, with the NYSE Health Care Index down 0.6% and the Health Care Select Sector SPDR Fund (XLV) shedding 0.5%.

The iShares Biotechnology ETF (IBB) rose 0.4%.

In corporate news, Tela Bio ( TELA ) shares tumbled past 38%, a day after the company reported Q1 and 2025 sales guidance that missed estimates by analysts.

Alnylam Pharmaceuticals ( ALNY ) shares jumped past 10%. The company said late Thursday the US Food and Drug Administration has approved a supplemental new drug application for Amvuttra to treat cardiomyopathy of wild-type or hereditary transthyretin-mediated amyloidosis in adults.

AstraZeneca ( AZN ) will invest $2.5 billion in a new research facility in Beijing just months after the company's top executive for China was detained by the country's authorities, Bloomberg reported. AstraZeneca ( AZN ) shares were shedding 2%.

Johnson & Johnson ( JNJ ) plans to increase US investments to more than $55 billion over the next four years to boost its manufacturing and research capabilities. Its shares were 0.2% lower.