11:09 AM EDT, 07/30/2025 (MT Newswires) -- European equities traded in the US as American depositary receipts were lower late Wednesday morning, declining 0.78% to 1,466.80 on the S&P Europe Select ADR Index.

From continental Europe, the gainers were led by medical device maker EDAP TMS ( EDAP ) and internet advertising firm Criteo ( CRTO ) , which climbed 7.4% and 4.6%, respectively. They were followed by biopharmaceutical company Grifols ( GRFS ) and furniture manufacturer Natuzzi (NTZ), which advanced 3.6% and 3.3%, respectively.

The decliners from continental Europe were led by pharmaceutical company Novo Nordisk ( NVO ) and petroleum refiner Equinor ( EQNR ) , which fell 5% and 3.8%, respectively. They were followed by electronics conglomerate Philips (PHG) and semiconductor company Sequans Communications ( SQNS ) , which dropped 3% and 2.5%, respectively.

From the UK and Ireland, the gainers were led by biotech firms Autolus Therapeutics ( AUTL ) and Trinity Biotech ( TRIB ) , which rose 6% and 5.2%, respectively. They were followed by pharmaceutical company GSK (GSK) and biopharmaceutical company Mereo BioPharma Group ( MREO ) , which were up 2.7% and 2.6%, respectively.

The decliners from the UK and Ireland were led by biopharmaceutical company NuCana ( NCNA ) and financial services company HSBC ( HSBC ) , which lost 9% and 4.6%, respectively. They were followed by oil and gas companies BP (BP) and Shell (SHEL), which were down 2% each.