10:59 AM EDT, 10/28/2025 (MT Newswires) -- European equities traded in the US as American depositary receipts were little changed late Tuesday morning, edging 0.01% lower to 1,604.02 on the S&P Europe Select ADR Index.

From continental Europe, the gainers were led by biotech firm Evaxion ( EVAX ) and telecommunications company Nokia ( NOK ) , which rose 4.5% and 1.7% respectively. They were followed by lender Banco Santander (SAN) and semiconductor company Sequans Communications ( SQNS ) , which were up 1.3% and 0.2% respectively.

The decliners from continental Europe were led by 3D printer company Materialise (MTLS) and accommodations booking site trivago (TRVG), which fell 2.1% and 1.8% respectively. They were followed by consumer goods giant Unilever ( UL ) and pharmaceutical company Sanofi ( SNY ) , which were down 1.6% and 1.1% respectively.

From the UK and Ireland, the gainers were led by lender HSBC ( HSBC ) and pharmaceutical company Silence Therapeutics ( SLN ) , which advanced 4% and 3.2% respectively. They were followed by biopharmaceutical companies Akari Therapeutics ( AKTX ) and Mereo BioPharma Group ( MREO ) , which increased 3.1% and 1% respectively.

The decliners from the UK and Ireland were led by cruise line operator Carnival (CUK) and biotech firm Autolus Therapeutics ( AUTL ) , which dropped 4.3% and 3.9% respectively. They were followed by biopharmaceutical companies Biodexa Pharmaceuticals ( BDRX ) and NuCana ( NCNA ) , which lost 3.3% and 1.2% respectively.