11:22 AM EDT, 04/09/2025 (MT Newswires) -- European equities traded in the US as American depositary receipts were trending lower late Wednesday morning, declining 0.9% to 1,215.82 on the S&P Europe Select ADR Index.

From continental Europe, the gainers were led by financial services companies Banco Bilbao Vizcaya Argentaria ( BBVA ) and Banco Santander (SAN), which rose 2.8% and 2% respectively, followed by software firm SAP (SAP), which was up 0.3%.

The decliners from continental Europe were led by biopharmaceutical companies Ascendis Pharma ( ASND ) and DBV Technologies ( DBVT ) , which dropped 7.7% and 5.6% respectively. They were followed by biopharmaceutical companies Genfit ( GNFT ) and argenx (ARGX), which lost 4.8% and 4.4% respectively.

From the UK and Ireland, the gainers were led by biopharmaceutical company NuCana ( NCNA ) and mining company BHP Group ( BHP ) , which climbed 8.3% and 2.2% respectively. They were followed by cruise line operator Carnival (CUK) and biopharmaceutical company Amarin ( AMRN ) , which increased 2% and 1% respectively.

The decliners from the UK and Ireland were led by biopharmaceutical companies Verona Pharma ( VRNA ) and Mereo BioPharma ( MREO ) , which fell 10.8% and 8.8% respectively. They were followed by biopharmaceutical company Biodexa Pharmaceuticals (BDRX) and biotech firm Trinity Biotech ( TRIB ) , which were down 2.8% and 0.8% respectively.