11:00 AM EDT, 10/01/2025 (MT Newswires) -- European equities traded in the US as American depositary receipts surged higher late Wednesday morning, climbing 1.42% to 1,583.79 on the S&P Europe Select ADR Index.

From continental Europe, the gainers were led by biopharmaceutical company Cellectis ( CLLS ) and biotech firm Evaxion ( EVAX ) , which advanced nearly 15% and 12%, respectively. They were followed by biopharmaceutical company DBV Technologies ( DBVT ) and pharmaceutical company Sanofi ( SNY ) , which rose 6.4% and 5.4%.

The decliners from continental Europe were led by brewing company Anheuser-Busch InBev ( BUD ) and lender Banco Santander (SAN), which lost 0.8% each. They were followed by lender Banco Bilbao Vizcaya Argentaria ( BBVA ) and consumer goods giant Unilever ( UL ) , which were off 0.4% each.

From the UK and Ireland, the gainers were led by pharmaceutical companies AstraZeneca ( AZN ) and GSK (GSK), which climbed 7.5% and 4.6%, respectively. They were followed by biopharmaceutical company Bicycle Therapeutics ( BCYC ) and biotech firm Trinity Biotech ( TRIB ) , which increased 3.8% and 2.9% respectively.

The decliners from the UK and Ireland were led by biopharmaceutical companies Akari Therapeutics ( AKTX ) and Adaptimmune Therapeutics ( ADAP ) , which dropped 1.8% and 1.4% respectively. They were followed by cruise line operator Carnival (CUK) and communications company WPP ( WPP ) , which were down 1.2% and 1% respectively.