(For a Reuters live blog on U.S., UK and European stock

markets, click or type LIVE/ in a news window)

March 27 (Reuters) - The UK's main stock indexes were on

track for a fourth straight week of losses on Friday, as

investors remained on edge due to uncertainty around the Middle

East conflict, and fears of a spike in inflation.

U.S. President Donald Trump announced a new extension of his

deadline for Iran to reopen the Strait of Hormuz or face the

destruction of its energy facilities, after Tehran rejected

Washington's 15-point proposal to end the war.

The blue-chip FTSE 100 index fell 0.7% at 1125 GMT,

while the midcap FTSE 250 fell 1.2%. Both indexes were

also headed for steep monthly losses.

* Most sub-sectors traded in the red, except healthcare

, which rose 1.6%, as positive late-stage trial

results for AstraZeneca's ( AZN ) experimental respiratory

treatment sent the drugmaker's shares up 2.9%.

* Lloyds Banking group ( LYG ) fell 1.9% after Britain's

Treasury Committee said an IT glitch earlier this month exposed

personal data of nearly half a million bank customers.

* Metlen fell 6% to the bottom of the benchmark

index after the Greek energy group delayed its FY25 results.

* Official data showed retail sales fell in February after

logging the strongest growth in a year and a half in January,

with Marchlikely to come under pressure as a war-driven surge in

oil prices weighs on households' disposable income.

* Meanwhile, British consumer sentimentfell to its

lowest level in nearly a year in March, a closely watched

monthly survey showed, as concerns over the economic fallout

from the Iran war and the prospect of sharp price rises kept

households on edge.