03:59 PM EST, 11/19/2025 (MT Newswires) -- Health care stocks fell late Wednesday afternoon with the NYSE Health Care Index easing 0.1% and the Health Care Select Sector SPDR Fund (XLV) decreasing 0.2%.

The iShares Biotechnology ETF (IBB) shed 0.7%.

In corporate news, Pfizer ( PFE ) and its supplier Tris Pharma reached a $41.5 million settlement with Texas Attorney General Ken Paxton for allegedly providing adulterated attention deficit hyperactivity disorder medication to children. Pfizer ( PFE ) shares dropped 2%.

Johnson & Johnson's ( JNJ ) Janssen Biotech unit has been granted traditional approval for Darzalex Faspro with bortezomib, cyclophosphamide, and dexamethasone for newly diagnosed light chain amyloidosis, the US Food and Drug Administration said. Johnson & Johnson ( JNJ ) shares rose 1.4%.

Moderna ( MRNA ) is onshoring drug product manufacturing to its Moderna Technology Center in Norwood, Massachusetts. The company said the move boosts its US commercial and clinical supply capabilities, and reflects more than $140 million in planned investment. The stock dropped 3%.

Agios Pharmaceuticals ( AGIO ) shares tumbled 51% after the company said its potential sickle cell disease treatment mitapivat failed to meet one of two primary endpoints in a 52-week Phase 3 trial.