GENEVA, July 29 (Reuters) - Bird flu vaccine developer
Sinergium Biotech will share its data with manufacturers in low
and middle-income countries to help to accelerate a fair rollout
if a pandemic occurs, the World Health Organization said on
Monday.
The Argentine private sector biopharmaceutical company is at
an early stage of developing mRNA vaccines against the H5N1
virus and has pledged to share its findings with a network of
partner manufacturers set up by the WHO during the peak of
COVID-19 to help poorer countries to gain access to life-saving
medical tools.
Until now, the WHO has assisted partners but this is the
first time one of them with a vaccine in development has
volunteered to share it with others.
"Partners interested in this will be able to start getting
their fingers wet, beginning to practise with an H5N1 candidate
so that if a pandemic was to start ... they would already have
the necessary tools in their facilities," said Dr Martin Friede,
head of the WHO vaccine research unit.
The WHO's mRNA technology transfer hub programme includes
manufacturers in 15 countries, though not all are fully
established. Among those involved in the programme are Biovac in
South Africa and Institut Pasteur in Senegal.
The South African centre was set up after global
pharmaceuticals companies including Moderna ( MRNA ) and Pfizer ( PFE )
declined to provide the technical know-how to replicate their
COVID vaccines, mainly owing to intellectual property concerns.
The outbreak of H5N1 in dairy cows and some farm workers in
the United States prompted Washington to award $176 million to
Moderna ( MRNA ) to advance development of its bird flu vaccine.
While the WHO has said the risk to the public from the
avian influenza virus remains low and that it is not spreading
between people, they say it has the potential to cause a future
pandemic because of its widespread circulation in animals.
While Friede acknowledges that the likes of Moderna ( MRNA ) and
Pfizer ( PFE ) would be able to produce vaccines much more quickly than
manufacturers in the WHO programme, he said that the scheme
would allow Sinergium's partners to begin production reasonably
quickly and help to keep poorer countries from being reliant on
handouts.
There are vaccines available for the H5N1 strain that is
spreading among cows in the United States, but they are mostly
made using chicken eggs, which means they would take months to
produce at scale if needed.
Sinergium's mRNA flu vaccine has yet to be tested in people,
the WHO said, so it would require human trials before use.
Moderna's ( MRNA ) mRNA H5N1 flu vaccine is further advanced, with
late-stage trials in humans expected to take place next year.