08:15 AM EST, 11/19/2025 (MT Newswires) -- Agios Pharmaceuticals ( AGIO ) shares were down 45% in Wednesday's premarket activity after it reported that its potential sickle cell disease treatment mitapivat failed to meet one of two primary endpoints in a 52-week phase 3 clinical trial. While the trial met its primary endpoint of hemoglobin response, mitapivat failed to show...

08:18 AM EST, 11/19/2025 (MT Newswires) -- Centuri ( CTRI ) said Wednesday it has completed the acquisition of Connect Atlantic Utility Services, positioning the company as a dual electric and gas services provider in Canada. Connect Atlantic Utility Services provides maintenance, construction, and storm restoration services to electric utility and developer clients in Canada's Atlantic provinces, Centuri ( CTRI...

08:18 AM EST, 11/19/2025 (MT Newswires) -- Main Street Capital ( MAIN ) said Wednesday that it recently completed a new portfolio investment of $27.2 million in Texas-based The Nearshore Company to facilitate its acquisition of the Carmi Companies. The investment entails a combination of first-lien, senior secured term debt and a direct minority equity investment, Main Street Capital (...

08:18 AM EST, 11/19/2025 (MT Newswires) -- Joby Aviation ( JOBY ) said Wednesday that it has signed a memorandum of understanding with Red Sea Global and The Helicopter Company to evaluate the deployment of its electric air taxi in Saudi Arabia in H1 of next year. The companies will establish a sandbox for pre-commercial operations, which will serve as...