July 17 (Reuters) - Roche said on Wednesday its
CT-996, a new drug being developed to treat obesity and type 2
diabetes, has had positive results for weight loss in phase one
of its clinical trial.
Roche is among a growing number of would-be rivals to Novo
Nordisk and Eli Lilly ( LLY ), whose weight-loss
drugs have caused a storm in demand as experts up their sales
forecasts for such treatments to as much as $150 billion by the
early 2030s.
Data for Roche's oral drug, to be taken once daily, showed
that treatment resulted in a placebo-adjusted mean weight loss
of 6.1% within four weeks, the Swiss drugmaker said in a
statement.
The drug "was well-tolerated, with mostly mild or moderate
gastrointestinal-related adverse events, consistent with the
safety profile of the incretin drug class," according to the
statement.
"We are pleased to see the clinically meaningful weight loss
in people treated with our oral GLP-1 therapy CT-996, which
could eventually help patients address both chronic weight
management and glycaemic control indications," Chief Medical
Officer Levi Garraway said.
Based on the phase-one results, CT-996 will advance into
phase-two clinical development, Roche said.
Roche shares indicated 2% higher on premarket.