Oct 8 (Reuters) - Zenas BioPharma ( ZBIO ) said on Wednesday it has
secured global rights to develop and commercialize an experimental drug from
China-based InnoCare Pharma for multiple sclerosis and other
autoimmune conditions under a licensing deal potentially worth more than $2
billion.
The deal grants Zenas worldwide rights to the drug, orelabrutinib, outside
oncology. The U.S.-based drug developer will pay up to $100 million in upfront
and near-term milestone payments and issue up to 7 million shares of common
stock to InnoCare.
The agreement also covers two additional drug candidates, both slated for
early-stage trials next year.
Orelabrutinib is being tested in a late-stage trial for a type of multiple
sclerosis, a chronic disease that affects the central nervous system, with
another due to begin in early 2026.
The total of the upfront payment, near-term milestone and potential
development and regulatory milestone payments, along with potential commercial
sales milestones across all three programs, exceeds $2 billion, Zenas said.
"With this transaction, we have established a balanced portfolio ... with
best-in-class blockbuster potential across multiple therapeutic areas," Zenas
CEO Lonnie Moulder said.
Orelabrutinib is already approved for types of blood cancer in China and
Singapore, where it is marketed as Yinuokai and Hibruka, respectively.
Zenas also announced a $120 million private placement to fund development of
the programs.