11:07 AM EDT, 08/13/2025 (MT Newswires) -- European equities traded in the US as American depositary receipts were higher late Wednesday morning, rising 0.98% to 1,510.27 on the S&P Europe Select ADR Index.

From continental Europe, the gainers were led by biopharmaceutical companies Genfit ( GNFT ) and Cellectis ( CLLS ) , which climbed 7.5% and 6.4%, respectively. They were followed by pharmaceutical company Novo Nordisk ( NVO ) and consumer goods giant Unilever ( UL ) , which advanced 2.4% and 2%, respectively.

The decliners from continental Europe were led by pharmaceutical company Ascendis Pharma ( ASND ) and internet browser company Opera (OPRA), which were down 0.8% and 0.6%, respectively. They were followed by internet advertising firm Criteo ( CRTO ) and oil and gas company TotalEnergies (TTE), which lost 0.5% and 0.2%, respectively.

From the UK and Ireland, the gainers were led by biopharmaceutical company Bicycle Therapeutics ( BCYC ) and software firm Endava ( DAVA ) , which rose 7.6% and 7.5%, respectively. They were followed by pharmaceutical company Silence Therapeutics ( SLN ) and biopharmaceutical company Mereo BioPharma Group ( MREO ) , which were up 5.9% and 4.5%, respectively.

The decliners from the UK and Ireland were led by biotech firms Trinity Biotech ( TRIB ) and Autolus Therapeutics ( AUTL ) , which fell 4.4% and 3.7% respectively. They were followed by tobacco company British American Tobacco ( BTI ) and biopharmaceutical company Biodexa Pharmaceuticals ( BDRX ) , which dropped 1.9% and 1.8%, respectively